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Archived Press Releases

9/8/2010 Hemispherx Biopharma to Present at the Rodman and Renshaw 12th Annual Healthcare Conference

9/8/2010 HEMISPHERX BIOPHARMA TO PRESENT NEW RETROVIRUS (XMRV) DATA AT 1ST INTERNATIONAL WORKSHOP ON XMRV AND CHRONIC FATIGUE SYNDROME (CFS)
…Retrovirus Positive CFS Patients Show Enhanced Response to Ampligen®, An Experimental Therapeutic, Relative to XMRV Negative Group


8/24/2010 HEMISPHERX SETTLES ALL SECURITIES CLASS ACTIONS Title

8/18/2010 Hemispherx Biopharma Awarded $188 Million Judgment against JCI
…Culmination of 6 Year Litigation Battle In U.S. Federal Courts


8/6/2010 HEMISPHERX BIOPHARMA, INC. 2nd QUARTER 2010 FINANCIAL RESULTS …Drug / Biologic Development Progress in North America, India and Japan

7/19/2010 The Indian Drugs Controller General Approves Start of Clinical Study of Hemispherx Biopharma’s Natural Interferon Product, Alferon N Injection®, in Hospitalized Flu Patients
. . . Clinical Sites Expected to Enroll Subjects During Monsoon Season


7/15/2010 Hemispherx Publishes Full Report of Three Year Joint Research Program at Japanese NIID
…..Full Report Setting Stage for Clinical Testing of Novel Flu Vaccine/Ampligen® Combination Now Available on Hemispherx’s Website


7/12/2010 Hemispherx Reports Successful Culmination of Three Year Joint Research Program at Japanese NIID
…..Sets Stage for Clinical Testing of Novel Flu Vaccine/Ampligen® Combination.


6/15/2010 Hemispherx Biopharma Licenses Platform Technologies to GP Pharm
.…Initial Commercial Target is Chronic Fatigue Syndrome in Latin America


5/17/2010 Hemispherx Biopharma Prepares Application to Initiate Phase II Clinical Trials in China with Ampligen®
. . . Proposed Trial to Address Seriously Ill Patients with Influenza


5/13/2010 Hemispherx Biopharma to Present at the Rodman Healthcare Conference

5/7/2010 HEMISPHERX BIOPHARMA, INC. 1st QUARTER 2010 FINANCIAL RESULTS

5/3/2010 New Independent Data Monitoring Committee Established by Hemispherx to Accelerate Global Drug Development

4/1/2010 Hemispherx Biopharma and Max Neeman International Team Initiate Influenza Research Programs
. . . Clinical Sites Targeted to Enroll Subjects Beginning in Upcoming Monsoon Season


3/23/2010 Stanford University Researcher and Hemispherx Biopharma Consultant Present New Integrative Immunotherapy Approach
……suggests that the safety and bioactivity of TLR3 agonists may be unique


3/15/2010 Hemispherx Biopharma Announces 2009 Financial Results
Cash and Cash Equivalent Increase 9 Fold over Prior Year


2/23/2010 Hemispherx Biopharma Acquires New Internet Domain Rights
...will provide new portals to access Ampligen®/Alferon® N information


2/11/2010 Hemispherx Announces Award of 2009 Executive Bonuses

2/8/2010 New Animal Model for Evaluating Antiviral Agents Against the SARS Virus Indicates Potential Effect of Ampligen®, an Experimental Therapeutic
...Independent University Researchers Find Ampligen® “Fully Protective” in Study


2/4/2010 Hemispherx Biopharma Appoints Two Senior Pharma Executives to Key Manufacturing Positions

2/2/2010 Hemispherx Biopharma Receives Favorable Notice Via Its Subcontractor That The FDA Seattle District Accepts Ampligen® Manufacturing Response

1/28/2010 Stanford University Publishes New Data on Immuno-potential of Hemispherx’s Ampligen®
….May Enhance Bioactivity of Cancer Immunotherapies


1/14/2010 Hemispherx Biopharma provides Grant to IACFS to assist in the Development of Chronic Fatigue Syndrome (CFS) Clinical Guidelines

1/14/2010 Hemispherx Biopharma Addresses Ampligen® CFS Preclinical Issues

12/16/2009 Hemispherx Biopharma Addresses Ampligen® Manufacturing Issues

12/2/2009 Hemispherx Biopharma Announces Investor Conference Call

12/1/2009 Hemispherx Biopharma Receives Complete Response Letter from FDA on Ampligen® New Drug Application for Chronic Fatigue Syndrome
…Outlines Additional Recommendations


11/16/2009 Class Action Lawsuit Against Hemispherx Biopharma Is Without Merit

11/9/2009 HEMISPHERX BIOPHARMA, INC. 3rd QUARTER 2009 FINANCIAL RESULTS
……Cash/Cash Equivalents Increase Almost 10 Fold And Net Loss For Quarter Reduced 29%


11/2/2009 Hemispherx Biopharma Updates Chronic Fatigue Syndrome (CFS) Treatment and Commercial Application Programs ......Targets Completion of All NDA Regulatory Responses and Initiation of Expanded Clinical Collaborations in CFS

10/26/2009 Japanese NIH Expands Pandemic Flu Protective Potential by Ampligen®
......New Publication Suggests Pandemic Vaccines Adjuvanted are More Effective; The Potential Importance of Antigen Sparing and Cross-Protective Formulations


10/15/2009 Japanese NIH Research Reaffirms and Expands Pandemic Flu Protection by Ampligen®
......New Data at recent “Mucosal Immunity” International Workshop in Osaka Suggest Alternative Method to Protect at High Risk Groups


10/13/2009 New Infectious Retrovirus Detected in Chronic Fatigue Syndrome
….May Clarify Mechanism of Action of Hemispherx’s Ampligen®


10/8/2009 Hemispherx’s Ampligen®/ Intranasal Flu Vaccine Program to be Presented at International Vaccine Workshop in Osaka
….Coincides with First Deliveries of Intranasal Pandemic Vaccine in U.S. to High Risk Groups


10/2/2009 Stanford University Presents New Data on Immuno-potential of Hemispherx’s Ampligen® ….May Enhance Bioactivity of Cancer Immunotherapies

9/24/2009 Japanese National Institute of Health to Present New Data on Hemispherx’s Vaccine Enhancer
....Emphasis on Prevention of Pandemic Influenza


9/23/2009 Hemispherx Presents at the Maxim Group Annual Growth Conference
....Emphasis on Prevention, Prophylaxis and Treatment of Influenza


9/16/2009 Hemispherx Board of Directors Authorizes Multimillion Dollar Expansion of its FDA Licensed Manufacturing Facilities
....Increases Capability to Expand Alferon LDOTM and Ampligen® for Various Influenza-Based Clinical and Commercial Production


9/2/2009 Hemispherx Biopharma Presents at the Rodman Healthcare Conference ....New Comparative Analysis on Alferon LDO in Pandemic Influenza

9/2/2009 Hemispherx Biopharma Announces Cancellation of Adjourned Stockholders’ Meeting

8/10/2009 HEMISPHERX BIOPHARMA, INC. 2nd QUARTER 2009 FINANCIAL RESULTS
Cash Position Increases Approximately 6.5 Fold and Influenza Studies Expand


7/22/2009 Hemispherx Biopharma Announces Further Adjournment on Proposal Number 3 from the 2009 Annual Meeting of Stockholders

7/20/2009 HEMISPHERX BIOPHARMA TO PROVIDE UPDATE ON GLOBAL PANDEMIC INFLUENZA PREVENTION / TREATMENT INITIATIVES

6/24/2009 Hemispherx Biopharma Reports on Annual Stockholder Meeting

6/17/2009 Hemispherx Biopharma appoints Robert Dickey IV to the new position of Senior Vice President
Role to facilitate strategic partnering and clinical progress


6/16/2009 Hemispherx Biopharma Provides Corporate Update on Various Strategic Initiatives

6/12/2009 Hemispherx’s Collaborative Partner in Japan, Biken Corp., Expands Production Capacity for Swine/Avian Flu Vaccines …WHO Raises Threat of Swine Flu to Pandemic Level

6/4/2009 Japanese National Institute of Infectious Diseases Scientists Identify Hemispherx Biopharma’s Drug Technology as the “Most Promising Mucosal Adjuvant for Influenza”
.....Topical Application Also Affords Strong Cross-Protection against Variant Flu Strains


6/1/2009 Hemispherx Biopharma Presents Influenza Prevention / Treatment Platform at International Conference in Rome under Auspices of Italian Government ….Company Accelerates Collaborations with Governmental, Academic and Pharmaceutical Groups to Prevent Pandemic Influenza

5/27/2009 Hemispherx Announces Payment of 2008 Executive Bonuses

5/26/2009 HEMISPHERX BIOPHARMA ANNOUNCES POSSIBLE BRIEF DELAY IN FDA ACTION ON AMPLIGEN® NEW DRUG APPLICATION

5/21/2009 Japan’s Council Awards Innovative Technology Grants for Pandemic Influenza Vaccines Adjuvanted by Hemispherx’s Ampligen® …“Super Special Consortia” to promote key technologies

5/19/2009 Hemispherx Biopharma Announces $16 Million Public Equity Offering

5/12/2009 HEMISPHERX BIOPHARMA, INC. 1st QUARTER 2009 FINANCIAL RESULTS
Operating Cash Requirements Reduced 49%


5/11/2009 Hemispherx Biopharma Announces $18.3 Million Public Equity Offerings

4/27/2009 Japanese Government Accelerates Hemispherx Biopharma’s Ampligen® Research Programs for Influenza Protection
…..Flu Virus Mutations May Limit Tamiflu Usefulness


3/17/2009 HEMISPHERX BIOPHARMA, INC. TO DISCUSS NEW CHRONIC FATIGUE SYNDROME CLINICAL DATA AND YEAR-END 2008 RESULTS ON MARCH 19, 2009

3/16/2009 HEMISPHERX BIOPHARMA, INC. ANNOUNCES 2008 FINANCIAL RESULTS
Multiple Commercial- Directed Programs Progress; Net loss Reduced 31%


2/18/2009 HEMISPHERX BIOPHARMA TO PRESENT NEW AMPLIGEN® CLINICAL DATA AT THE 9TH INTERNATIONAL IACFS/ME CONFERENCE

Clinical/lab Parameters of Potential Special Import to CFS Disease Severity


2/18/2009 FDA EXTENDS HEMISPHERX’S NDA REVIEW DATE FOR AMPLIGEN® AS POTENTIAL TREATMENT FOR CFS

Extended User Fee Goal is now May 25, 2009


1/5/2009 U.S. Court of Appeals Supports Hemispherx in Rebuff of Hostile Takeover Attempt

12/4/2008 Hemispherx Biopharma Announces New Chief Financial Officer

11/28/2008 ATTORNEY THOMAS EQUELS ELECTED TO HEMISPHERX BIOPHARMA BOARD OF DIRECTORS

11/28/2008 Hemispherx Biopharma Introduces Expense Reduction Program ……Medical, Regulatory, Manufacturing Operations Remain Intact

11/18/2008 Hemispherx Enters Major Contract with Lovelace Respiratory Institute
…..Projected New Data to Enhance Ampligen® NDA Filing Status in Chronic Fatigue Syndrome


11/10/2008 HEMISPHERX BIOPHARMA, INC. RELEASES FINANCIAL RESULTS FOR THE THREE MONTHS ENDED SEPTEMBER 30, 2008
….Net Loss Reduced 40% over Prior Year


10/28/2008 Hemispherx Selected to Present at 7th Annual BIO Investor Forum
…..Showcases Leading Growth Companies in Life Sciences


10/28/2008 Hemispherx Selected to Present at 7th Annual BIO Investor Forum
…..Showcases Leading Growth Companies in Life Sciences


10/27/2008 Immune Adjuvants and Cancer Vaccines: Hemispherx’s New Enhancement Strategy
…….To be Unveiled at Upcoming 23rd Annual Biotherapy Conference


10/23/2008 Nobel Laureate Confirms Importance of Adjuvants in Controlling Devastating Diseases
……Hemispherx’s Adjuvant Portfolio among the Most Studied at Clinical Level


10/21/2008 HEMISPHERX BIOPHARMA TO PRESENT AT 48th ANNUAL ICAAC CONFERENCE
…Presentation Highlights Pending NDA Data for Treating CFS


10/17/2008 HEMISPHERX BIOPHARMA, INC. ADJOURNS STOCKHOLDER MEETING TO NOVEMBER 11, 2008

10/9/2008 HEMISPHERX SCIENTIFIC ADVISORY BOARD MEMBER, DR. LUC MONTAGNIER, RECEIVES NOBEL PRIZE FOR MEDICINE Director of the World Foundation for AIDS Research and Prevention Advocates Investigation of Widespread Use of Alferon LDO to Combat Life-Threatening Viral Infections

10/6/2008 HEMISPHERX ENGAGES THE SAGE GROUP AS ITS CORPORATE PARTNERSHIP ADVISOR FOR AMPLIGEN® TO TREAT CHRONIC FATIGUE SYNDROME

9/30/2008 HEMISPHERX TO PRESENT DATA AT “SECOND WORLD CONFERENCE ON MAGIC BULLETS (ERLICH II)”

9/23/2008 JAPANESE NIH SCIENTISTS REPORT ROBUST CROSS-PROTECTION WITH HEMISPHERX DRUG AGAINST MULTIPLE STRAINS OF BIRD FLU . . . Findings Coincide with Newly Reported Bird Flu Epidemic in Northern Japanese Swans.

9/17/2008 HEMISPHERX BIOPHARMA, INC. ADJOURNS STOCKHOLDER MEETING DUE TO LACK OF A QUORUM TO OCTOBER 17, 2008

9/3/2008 HEMISPHERX BIOPHARMA TO PRESENT AT BIOPHARM AMERICA CONFERENCE …Accelerates Commercial Focus with Multiple Registration Targets, Including Vaccine Enhancement

8/12/2008 HEMISPHERX BIOPHARMA, INC. RELEASES FINANCIAL RESULTS FOR THE THREE MONTHS ENDED JUNE 30, 2008
. . . Programs Accelerate in United States, Japan and Australia


7/15/2008 HEMISPHERX BIOPHARMA TO HOST INVESTOR CONFERENCE CALL ON CHRONIC FATIGUE SYNDROME NDA FILING
Discussion to also address other corporate initiatives


7/14/2008 Hemispherx Biopharma, Inc. Announces Settlement of All Bioclones/Ribotech Litigation
Discussions in progress for potential future partnership in HIV/AIDS and Hepatitis


7/8/2008 Hemispherx Biopharma’s Ampligen® NDA for Chronic Fatigue Syndrome Accepted for Review by the FDA
Marks the first drug candidate for approval to treat CFS, and the first compound in the TLR class


6/16/2008 Hemispherx Biopharma, Inc. Announces Settlement of Arbitration with Laboratorios del Dr. Esteve
Hemispherx regains licensing rights in Spain, Portugal and Andorra


6/2/2008 Hemispherx Biopharma, Inc. Completes Enrollment in Phase II Study of Ampligen® as Seasonal Flu Vaccine Enhancer
Six-month study will also assess potential cross-protection against H5N1 avian influenza


5/13/2008 HEMISPHERX BIOPHARMA, INC. RELEASES FINANCIAL RESULTS FOR THE THREE MONTHS ENDED MARCH 31, 2008
….Losses reduced by 38% over prior 2007 period; Progress made with Three Platform Technologies


4/7/2008 HEMISPHERX BIOPHARMA TO HOST INVESTOR CONFERENCE CALL
Discussion to focus on Year-end 2007 Financials, Chronic Fatigue Syndrome NDA Update, and Corporate Initiatives for 2008


4/7/2008 HEMISPHERX BIOPHARMA, INC. ACCELERATES AMPLIGEN® AS A POTENTIAL ADJUVANT FOR BOTH AVIAN INFLUENZA AND HIV VACCINES
New Approach Produces Robust Immunity to Overcome Therapeutic Obstacles


3/18/2008 HEMISPHERX BIOPHARMA, INC. ANNOUNCES 2007 FINANCIAL RESULTS
………Net loss decreases over year 2006


3/6/2008 HEMISPHERX BIOPHARMA REACHES AGREEMENT WITH FDA ON SPECIFIC STEPS TO ACHIEVE COMPLETE NDA ON PROPOSED CFS TREATMENT
… No Additional Studies Indicated


2/26/2008 Hemispherx Biopharma to Present at Jesup & Lamont Conference

2/11/2008 Hemispherx Biopharma to Present at New York Bio Conference

1/9/2008 Hemispherx Biopharma Addresses FDA Questions On Ampligen NDA
First 'TLR' Drug Candidate for Systemic Use


12/27/2007 Hemispherx Announces Executive Bonuses

12/27/2007 Hemispherx’s CFS Clinical Programs Reviewed in European Community
United Kingdom report focuses on Chronic Fatigue Syndrome and Ampligen®, an experimental therapeutic


12/19/2007 Hemispherx Biopharma Comments on 2005 BDO Audit News
BDO Internal Deficiencies Did Not Involve Hemispherx Personnel and Financial Statements Improved upon Reissuance


12/17/2007 HEMISPHERX BIOPHARMA ANNOUNCES INVESTORS CONFERENCE CALL
Discussion to focus on Vaccine Licensing agreements and updates on CFS filing status


12/13/2007 HEMISPHERX BIOPHARMA ANNOUNCES LICENSING/ RESEARCH AGREEMENTS ON AMPLIGEN® AS INFLUENZA ADJUVANT WITH JAPAN’S BIKEN
FACILITATES BIRD FLU VACCINE DEVELOPMENT FUNDED BY JAPANESE GOVERNMENT


12/10/2007 HEMISPHERX BIOPHARMA INTENDS TO TERMINATE LICENSE TO ESTEVE FOR THE MARKETING OF AMPIGEN® FOR CHRONIC FATIGUE SYNDROME (CFS) IN CERTAIN TERRITORIES
Company Expects to Regain Marketing Rights in Spain, Portugal and Andorra


12/8/2007 HEMISPHERX BIOPHARMA ANNOUNCES INVESTORS CONFERENCE CALL
Discussion to focus on NDA Filing Status


12/7/2007 HEMISPHERX BIOPHARMA RECEIVES NOTICE OF INCOMPLETE NEW DRUG APPLICATION (NDA)
Company Expects to Respond Promptly while Moving Forward on Planned Filings outside the U.S.


12/6/2007 Hemispherx Biopharma to Present at the NYSSA 11th Annual Biotech/Specialty Pharma Conference
Updates Provided on Global Initiatives


11/29/2007 HEMISPHERX BIOPHARMA ANNOUNCES CHANGE IN AUDIT COMMITTEE

11/12/2007 Japan Institute of Infectious Diseases Publishes Second Article on Ampligen® as Avian Flu Vaccine Immune Enhancer
Data Supports Potential Extension of H5N1 Vaccine Supplies by Means of Co-Administration with Hemispherx Biopharma’s Ampligen®


11/8/2007 HEMISPHERX BIOPHARMA ANNOUNCES INTERIM FINANCIAL RESULTS FOR THE THREE MONTHS ENDED SEPTEMBER 30, 2007
With Debt Retired in July and NDA for Ampligen® to Treat CFS Filed in October, Focus is On Anticipated Drug Development Milestones


10/31/2007 HEMISPHERX BIOPHARMA PRESENTS AT RODMAN & RENSHAW 9th ANNUAL HEALTHCARE CONFERENCE
Expands on Commercialization progress with TLR3 based Therapeutics


10/18/2007 Japan Institute of Infectious Diseases Publishes Article on Ampligen® as Avian Flu Vaccine Immune Enhancer
Hemispherx Biopharma’s Ampligen® Plus Seasonal Influenza Vaccine Yields Encouraging Data on Pandemic Potential Control


10/11/2007 Hemispherx Biopharma Files New Drug Application for Ampligen® as Treatment of Chronic Fatigue Syndrome
NDA of investigational drug includes four well-controlled trials, more than 1,200 trial subjects and 90,000 doses


9/10/2007 Japan’s National Institute of Infectious Diseases Widens Research on Hemispherx’s Ampligen®, An Immune Enhancer, Co-Administered with a Vaccine in AIDS Research
Intranasal Vaccination for HIV-1 Utilizing Ampligen® as an Immuno Enhancer Holds Promise


8/27/2007 Hemispherx Biopharma Accelerates Enrollment in West Nile Virus Controlled Trial of Alferon N™ as Cases Increase Nationwide
• Also Announces Increase in Revenues from Alferon N Injection® HPV Indication Under Armada Specialty Pharmacy Agreement


7/2/2007 Hemispherx Biopharma Retires All Outstanding Debentures

6/26/2007 Hemispherx Biopharma Initiates Phase IIb Trial in Australia for Ampligen as Vaccine Adjuvant for Seasonal Influenza
…Goal is to Evaluate Immune Augmentation and Possible Cross-Protection by TLR Ligand Ampligen®


5/31/2007 Hemispherx Presents Potential Avian Influenza Treatment Breakthrough at Paris Conference
Alferon-LDO Primate Results Suggest Potential to Treat Healthcare Workers and “First Responders” in HPAI Outbreak


5/22/2007 Hemispherx to Present New Therapeutic Results at Paris Anti-Avian Influenza Conference
Existing therapy may be significantly improved; pneumonia may be mitigated.


5/11/2007 HEMISPHERX BIOPHARMA ANNOUNCES FIRST QUARTER 2007 FINANCIAL RESULTS
Quarterly Loss Decreases as Cash Reserves Increase


5/10/2007 HEMISPHERX BIOPHARMA TO PRESENT AT RODMAN & RENSHAW 4th ANNUAL GLOBAL HEALTHCARE CONFERENCE

4/30/2007 New Report Illuminates Ampligen®’s Unique Mechanism of Action
Hemispherx Biopharma’s Proprietary Experimental Therapeutic Activates TLR-3 Receptor to Potentiate Broad-Spectrum Immune Response


4/23/2007 Hemispherx and Armada Health Care enter Agreement to Launch Alferon N Injection® via Specialty Pharmacy Network
Utilizing SP Capabilities to Facilitate Expanded Access to Biotech Drugs


4/19/2007 HEMISPHERX BIOPHARMA ANNOUNCES INVESTORS CONFERENCE CALL
Discussion to focus on Year-end 2006 Financials, CFS NDA Program Update, the Japan initiative and New Strategic Directions


4/12/2007 Japanese Ministry Awards Grant to advance studies with Influenza Vaccines co-administered with Hemispherx’s Ampligen®
Studies indicate Ampligen’s® ability to increase efficacy of Influenza Vaccines across various strains


3/19/2007 HEMISPHERX BIOPHARMA ANNOUNCES 2006 FINANCIAL RESULTS
….Infrastructure and Financial Resources Increase as Potential Commercial Opportunities Emerge


2/14/2007 Hemispherx Avian Flu Prevention/Treatment Program Announces New Primate Results and Expands in both Europe and Southern Hemisphere
Experimental Treatment Designed to Prevent/Treat Multiple H5N1 Classes with Oral Non-Toxic Treatment


1/23/2007 Hemispherx Biopharma to Present at The Roth Capital Partners 19th OC Conference in Dana Point, California

12/12/2006 Hemispherx Comments on Chronic Fatigue Syndrome Initiatives by the Centers for Disease Control

11/28/2006 Hemispherx Biopharma Hires New President/Chief Operating Officer to Lead the Company’s Drive to Commercialization

11/9/2006 Hemispherx Biopharma Appoints McGladrey & Pullen as Independent Auditing Firm

11/6/2006 HEMISPHERX BIOPHARMA ANNOUNCES THIRD QUARTER 2006 RESULTS AND STRATEGIC UPDATE
•Strategic update conference call and webcast scheduled for Wednesday, November 15, 2006 on RNA based therapeutics.


10/30/2006 Hemispherx Biopharma to Present at Rodman & Renshaw Healthcare Conference, November 6th
Emphasis Placed on Advances with Chronic Fatigue Syndrome


10/23/2006 Researchers at Japanese National Institute of Infectious Diseases Present New Data on Hemispherx’s Vaccine Enhancement Platform
First Demonstration that Intranasal Administration of Ampligen®, Combined with H5N1 Vaccine, Will Induce Broad Cross-Protective Mucosal Immunity


10/19/2006 Hemispherx Biopharma Will Present at Urchin Capital Partners “Value Below the Radar 2006” Investor Conference on October 24, 2006 in San Francisco

10/16/2006 Hemispherx Biopharma’s Vaccine Enhancement Platform to be Presented at the Second International Conference on Influenza Vaccines for the World Researchers at Japanese National Institute of Infectious Diseases to Present New Data

9/21/2006 HEMISPHERX BIOPHARMA TO PRESENT AT 8TH INTERNATIONAL IACFS CONFERENCE ON CHRONIC FATIGUE SYNDROME, FIBROMYALGIA, RELATED ILLNESSES Successful Transfer of Technology to Expand Drug Production Announced

9/18/2006 HEMISPHERX BIOPHARMA TO PRESENT AT Fall 2006 Micro Cap Conference

8/29/2006 Hemispherx Biopharma Acquires New Technology to Advance DNA-Based Vaccine Production

8/16/2006 HEMISPHERX BIOPHARMA TO HOST QUARTELY CONFERENCE CALL Management to provide update on status of Active NDA Preparation and Avian Influenza Programs

8/14/2006 HEMISPHERX BIOPHARMA SECOND QUARTER 2006 EARNINGS ANNOUNCED Cash and Cash Equivalents Increased $5.3 Million for Six Months ended June 30, 2006

8/1/2006 Hemispherx Biopharma Announces Purchase of Royalty Interest from Stem Cell Innovations, Inc. Only Natural Alpha Interferon Product on the U.S. Market

7/27/2006 Hemispherx Biopharma Wins AMEX Compliance Approval, Looks Ahead to Promising Pharmaceutical Line-Up

7/6/2006 Science News Cover Story Highlights Hemispherx Biopharma in New Insights Confronting Chronic Fatigue Syndrome Promising Experimental Medicine is Designated First Specific Drug Candidate for CFS

6/30/2006 HEMISPHERX BIOPHARMA FIRST QUARTER 2006 EARNINGS ANNOUNCED

6/27/2006 Hemispherx Biopharma to Present at the The First International Conference on Avian Influenza in Humans At the Pasteur Institute Novel Therapeutic Approach Attacks Virus at 3 Levels Simultaneously

6/15/2006 HEMISPHERX BIOPHARMA TO PRESENT AT THE RODMAN & RENSHAW 3RD ANNUAL SECURITY, BIODEFENSE & CONNECTIVITY INVESTOR CONFERENCE Company’s Biodefense Shield and Avian Influenza Program Highlighted

6/12/2006 Hemispherx Biopharma Advances Influenza Vaccine/Immunopotentiation Clinical Trials Designed to Increase Vaccine Dosage Supply and Increase Cross-Protection Australian Clinical Protocol Complete

6/5/2006 HEMISPHERX BIOPHARMA Files Amended 10-K for 2005 and Announces Restatement of Financials for 2003 and 2004 Impact to Statement of Operations is an Increase in Net Loss Applicable to Common Stockholders of $.01 per share in 2003 and a Decrease of $0.07 in 2004 for an Accumulative Net Decrease in Loss Applicable to Common Stockholders of $2,777,000 for these Periods

5/15/2006 Hemispherx Biopharma Announces Influenza Vaccine/Immunopotentiation Clinical Trials Designed to Increase Vaccine Dosage Supply and Increase Cross-Protection

5/12/2006 Hemispherx Announces Approval by AMEX of Plan to Achieve Compliance Status

5/3/2006 Hemispherx Biopharma to Present Audited Results of Ampligen® Clinical Trials on Chronic Fatigue Syndrome at 5th International Conference on HHV; Studies Show Medically Significant Improvements Among CFS Patients

4/25/2006 Hemispherx Biopharma Announces Retention of New Senior Personnel and Contractors Ahead of Key NDA Filing for Chronic Fatigue Syndrome Treatment
New Management and R&D Team to Build on Critical Research on CFS Just Unveiled by Centers for Disease Control


4/13/2006 Letter to Shareholders of Hemispherx Biopharma, Inc. from William A. Carter, M.D., Chairman of the Board and Chief Executive Officer

4/11/2006 HEMISPHERX BIOPHARMA TO HOST CONFERENCE CALL TO REVIEW COMPANY’S ACCOMPLISHMENTS, UPDATE ON INFLUENZA RELATED STUDIES AND OUTLINE FUTURE GOALS

4/7/2006 Hemispherx Biopharma, Inc. Late Filing of Form 10-K Generates Standard Non-Compliance Notification From The AMEX

4/3/2006 Hemispherx Biopharma, Inc. Announces Delay in Filing Its Form 10-K for the Fiscal Year Ended December 31, 2005

3/16/2006 New Research From Hemispherx Biopharma Leverages Recent Studies to Identify Factors in Breakdown of Immune System; May Help Prevent Spread of Avian Flu
Results to be presented at the VIII International Symposium on Respiratory Viral Infections March 16-19 in Hawaii
Japanese researchers initiate primate studies with co-administration of Hemispherx Biopharma’s Ampligen and H5N1 vaccine


2/16/2006 3 New Studies Show Hemispherx Biopharma’s Ampligen® and Alferon® LDO May Provide Defense Against Avian Flu
Tests Indicate Potential of Ampligen® As Vaccine Adjuvant, Boosts Existing Drugs Tamiflu®, Relenza® Up To 100 Times; Alferon® LDO Found to Stimulate Production of Interferon, Offering Natural Defense Against Virus
Consortium of Researchers to Present Findings at Today’s ASM Biodefense Research Meeting in Washington, D.C.


1/3/2006 HEMISPHERX BIOPHARMA LETTER TO SHAREHOLDERS

12/20/2005 Hemispherx to Present at the 4th Annual Biodefense Research Meeting Sponsored by the American Society of Microbiology,
Ampligen® and Alferon® in Global Clinical / Animal Trials Against Avian Influenza


12/13/2005 Hemispherx Highlighted in Study of Innate Immunity As a Defense Against Bio-terror Threats,
Ampligen® and Alferon® featured in the December 2005 Journal of Allergy and Clinical Immunology


12/12/2005 HEMISPHERX BIOPHARMA TO PRESENT AT THE NEW YORK SOCIETY OF SECURITY ANALYSTS 9TH ANNUAL HEALTHCARE INDUSTRY CONFERENCE
New Influenza Treatment / Prevention Initiatives Introduced


11/29/2005 Hemispherx Biopharma Enters Research Agreement with Defence R&D Canada
Efficacy Evaluation of Ampligen® and Alferon® for the Prophylaxis of Human Respiratory Influenza Virus Infection


11/8/2005 HEMISPHERX BIOPHARMA THIRD QUARTER 2005 EARNINGS ANNOUNCED
…. Net Loss Decreases 59% in Current Quarter


11/4/2005 Ampligen® Currently Administered to 750 “Very Ill” Patients Annually

11/3/2005 Studies Continue to Highlight Hemispherx’s Ampligen® as Broadly Effective Adjuvant to Avian Influenza Treatments Ampligen® Demonstrates Strong Therapeutic Synergy with Relenza®

10/26/2005 Ampligen® Studies on Combinational Treatments Against Avian Influenza are Extended Tamiflu Resistant Strains are Reported in Asia

10/10/2005 Hemispherx Biopharma signs Letter of Intent with HollisterStier Laboratories LLC for the Production of Ampligen®

10/3/2005 Hemispherx Biopharma Signs Research Agreement with Japanese National Institute of Infectious Disease
Ampligen® sought as adjuvant for nasal flu vaccine


9/6/2005 Ampligen ® Enhances the Effectiveness of Tamiflu Against Avian Influenza
Second Independent Preclinical Study Confirms dsRNA Increases Flu Vaccine Effectiveness


9/1/2005 Hemispherx Biopharma Expands Manufacturing Facility for Production of Ampligen ® Status of clinical Trial advancements for Alferon LDO and manufacturing programs updated in stockholder letter

8/10/2005 HEMISPHERX BIOPHARMA SECOND QUARTER 2005 EARNINGS ANNOUNCED
…. Net Loss Decreases By 36% in Current Quarter


7/6/2005 New Government Sponsored Research Points to Gene Malfunction in Chronic Fatigue Syndrome (CFS) ....Exercise Induced Malfunction in Genes Provides New Potential Insight into Mechanism of Ampligen® Phase III Clinicals; Exercise Treadmill Improvement as Primary Efficacy Endpoint

5/16/2005 Alferon LDO Now in Human Clinical Trials As Experimental Antiviral/Immunodulatory Therapy
…. Accelerated evaluation of a synergistic cocktail of eight different alpha-interferons to potentially trigger “guardian angel” genes


5/16/2005 Alferon LDO Now in Human Clinical Trials As Experimental Antiviral/Immunodulatory Therapy … Accelerated evaluation of a synergistic cocktail of eight different alpha-interferons to potentially trigger “guardian angel” genes

5/11/2005 HEMISPHERX BIOPHARMA FIRST QUARTER 2005 EARNINGS ANNOUNCED …. Net Loss Decreases By 62% in Current Quarter

5/3/2005 Chronic Fatigue Syndrome Presented at Symposium in New York

4/11/2005 Hemispherx Biopharma’s Investigational Drug Increases Physical Performance in New Chronic Fatigue Syndrome (CFS) Clinical Study
Maximum oxygen consumption increased 10-fold with Ampligen® vs. Placebo


3/30/2005 Hemispherx Biopharma to Present New Phase III Results in Chronic Fatigue Syndrome Treatment at 18th International Conference on Antiviral Research

3/21/2005 Hemispherx Biopharma Inc. Appoints Steven D. Spence to the Board of Directors
Former Managing Director of Merrill Lynch appointed to Executive and Audit Committees


2/24/2005 Hemispherx Biopharma’s Alferon N® Highlighted as Potential New Therapy for Avian Influenza on CNBC’s “Closing Bell”
“Battling the Bird Flu” Segment Features Microcap Company as Contender in the Avian Flu Drug Manufacturing Race


2/14/2005 HEMISPHERX BIOPHARMA, INC. ELECTS PRESIDENT AND CHIEF OPERATING OFFICER …Experienced Executive in Business Development of Biopharmaceuticals

2/7/2005 HEMISPHERX BIOPHARMA EXPANDS EVALUATION OF ALFERON N AGAINST AVIAN FLU Promising Effects In Bird Populations To Be Expanded based on WHO/UN Findings ….New Goal is Slow Disease, Minimize Risks; Eradication Looks Unlikely.

1/3/2005 HEMISPHERX BIOPHARMA INITIATES ENROLLMENT IN HIV/HEP-C CLINICAL PROGRAM Clinical Trial with Ampligen In Collaboration With Esteve Laboratorios Targets HIV/HEP-C Twin Epidemics

12/27/2004 HEMISPHERX BIOPHARMA FILES LAWSUIT IN FEDERAL COURT ALLEGING CONSPIRACY BY FOREIGN NATIONALS TO MANIPULATE ITS STOCK PRICE AND ENGAGE IN ILLEGAL HOSTILE TAKEOVER Members of conspiracy group already under criminal investigation for stock fraud outside United States

12/21/2004 Los Angeles Times Article Focuses on Hemispherx Biopharma’s Experimental Drug Ampligen as a Potential New Therapy for Chronic Fatigue Syndrome
Prominent Experts on Chronic Fatigue Syndrome Comment in Article


11/22/2004 HEMISPHERX BIOPHARMA INITIATES ALFERON LDO® CLINICAL PROGRAM IN COLLABORATION WITH PRINCESS MARGARET HOSPITAL IN HONG KONG
Experimental Effort to Prevent Sudden Spread of Dreaded Viruses in Large, At Risk Populations


11/12/2004 HEMISPHERX BIOPHARMA THIRD QUARTER 2004 EARNINGS ANNOUNCED
…….Total Stockholders’ Equity Increases Approximately 146% in First 9 Months


11/8/2004 HEMISPHERX BIOPHARMA TO PRESENT AT THE NEW YORK SOCIETY OF SECURITY ANALYSTS 8TH ANNUAL HEALTHCARE INDUSTRY CONFERENCE

11/1/2004 Hemispherx Biopharma Presented New Data at the 44th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy in Washington, D.C.

10/25/2004 HEMISPHERX BIOPHARMA TO PRESENT AT THE RODMAN & RENSHAW TECHVEST 6TH ANNUAL HEALTHCARE CONFERENCE ON OCTOBER 27th

10/20/2004 Unexpected Neurological Damage Spreads with West Nile Virus; Heightens Concern in Healthcare Community
• Hemispherix Biopharma Actively Enrolling Patients in the Only Existing National Clinical Trial of a New Therapeutic Agent


10/18/2004 Hemispherx Biopharma Comments on Recent Release of Data on Primary Endpoint in Phase III Chronic Fatigue Syndrome Study
•Treadmill Improvement is Standard for Evaluating Chronic Fatigue Syndrome and other Disabling Conditions •Ampligen® Results Achieved Over Twice the Minimum Improvement Considered Medically Significant


10/11/2004 HEMISPHERX BIOPHARMA PRESENTS NEWPHASE III DATA ON AMPLIGEN® AT THE 7th INTERNATIONAL CONFERENCE FOR CHRONIC FATIGUE SYNDROME
Treadmill Improvement Data Exceeds Initial Indications; Patients Receiving Ampligen Perform at Twice the Level Historically Considered Medically Significant In Chronic Diseases


9/27/2004 Hemispherx Biopharma to Present New Data on Activity of Ampligen in Treating Chronic Fatigue Syndrome at Annual CFS Conference
Compares Activity of Ampligen(R) to Alzheimer Drug for Potential Treatment


9/9/2004 Griffin Securities Initiates Research Coverage of Hemispherx Biopharma With Buy Rating

9/7/2004 HEMISPHERX BIOPHARMA REPORTS COMMENCEMENT OF TREATMENT OF WNV

8/10/2004 HEMISPHERX BIOPHARMA SECOND QUARTER 2004 EARNINGS ANNOUNCED Cash Position and the Total Shareholders’ Equity Increased

8/6/2004 HEMISPHERX BIOPHARMA, INC. ANNOUNCES COMPLETION OF PRIVATE PLACEMENT

8/5/2004 Hemispherx Biopharma To Announce Second Quarter Financial Results and to Update Clinical Activities on Wednesday, August 11th
Company to Hold Conference Call and Webcast for Investors at 9 a.m. that day


8/2/2004 HEMISPHERX BIOPHARMA ANNOUNCES PRIVATE PLACEMENT OF COMMON STOCK AND WARRANTS

8/2/2004 HEMISPHERX BIOPHARMA TO REPORT NEW DATA ON PIVOTAL PHASE III STUDY IN CFS …..Hemispherx Expands Pivotal Study Results at Upcoming 44th ICAAC Meeting

7/21/2004 HEMISPHERX BIOPHARMA REPORTS ON WEST NILE VIRUS . . . Alferon-N Well-Controlled Clinical Trial Accelerates by New Human Cases of WNV Now Reported in Twelve States

7/20/2004 HEMISPHERX BIOPHARMA RECEIVES FDA AUTHORIZATION FOR CLINICAL TRIAL IN MULTIPLE SCLEROSIS
Trial Approved for Patients in Resistant / Intolerant MS Group


7/7/2004 HEMISPHERX BIOPHARMA INITIATES HIV/HEP-C CLINICAL PROGRAM
Clinical Trial with Ampligen In Collaboration With Esteve Laboratorios Targets HIV/HEP-C Twin Epidemics


6/24/2004 HEMISPHERX BIOPHARMA COMPLETES CORPORATE GOVERNANCE CERTIFICATION Company Fully Complies with the AMEX Corporate Governance Requirements

6/14/2004 HEMISPHERX BIOPHARMA LAUNCHES MULTIPLE SCLEROSIS SALVAGE PROGRAM WITH NATURAL INTERFERONS
Urgent Clinical Need for Alternative Therapy in the Resistant / Intolerant MS Group


6/1/2004 HEMISPHERX BIOPHARMA RECEIVES APPROVAL FOR WEST NILE VIRUS PROTOCOL WITH ALFERON N TREATMENT
Leading New York Hospital Approves Protocol for First National Clinical Trial


5/17/2004 HEMISPHERX FILES EXPANDED U.S. PATENT APPLICATION FOR TREATING SARS AND EMERGING VIRUSES Expanded Application includes Unique Oral Delivery Mechanism

5/14/2004 HEMISPHERX BIOPHARMA FIRST QUARTER 2004 EARNINGS ANNOUNCED …Cash Position Increases / GMP Manufacturing Capabilities Acquired

5/10/2004 HEMISPHERX BIOPHARMA LAUNCHES NEW HIV CLINICAL PROGRAM IN AFRICA WITH COST EFFECTIVE ANTIVIRAL DELIVERY
Key Collaboration with the World Foundation Aids Research and Prevention


5/3/2004 HEMISPHERX BIOPHARMA ANNOUNCES PHASE 3 CHRONIC FATIGUE SYNDROME TRIAL MEETS PRIMARY ENDPOINT
Patients Receiving Ampligen Improve at Twice the Level Considered Medically Significant


4/30/2004 Hemispherx Biopharma Accelerates Release Date on Phase 3 Data for Ampligen in CFS
Primary Endpoint Data for Ampligen to be Presented at 17th International Conference on Antiviral Research on May 3rd instead of May 6th


4/20/2004 HEMISPHERX BIOPHARMA CEO TO PRESENT AT WHITE MOUNTAIN CAPITAL BIOTECHNOLOGY CONFERENCE Background on New Phase 3 Clinical Data on CFS to be Presented

4/19/2004 HEMISPHERX BIOPHARMA REPORTS PUBLICATION SHOWING SUPERIOR ACTIVITY OF ALFERON AGAINST SARS Alferon Highest Activity Against SARS Among 19 Clinically Approved Compounds

4/13/2004 Hemispherx Biopharma to Present First Phase 3 Data on Ampligen in Chronic Fatigue Syndrome at the 17th International Conference on Antiviral Research Primary Endpoint Data Presented at International Conference to be Held May 2-6, 2004

3/18/2004 Hemispherx Biopharma Completes Acquisition for Worldwide Rights to Alferon N
Company Closes Final Agreement on GMP Certified Manufacturing Facility; Expects International Sales to Begin During the Second Quarter


3/15/2004 HEMISPHERX BIOPHARMA REPORTS 2003 YEAR-END RESULTS Cash Position and Total Shareholder’s Equity Increases

3/2/2004 HEMISPHERX BIOPHARMA ANNOUNCES FDA AUTHORIZATION FOR A CLINICAL STUDY WITH NEW BIOLOGICAL ALFERON LDO FOR HIV
Company to Initiate Phase II Study in early-stage HIV Patients


2/25/2004 HEMISPHERX BIOPHARMA TO PRESENT AT WALL STREET ANALYST FORUM ON MARCH 1st

2/18/2004 HEMISPHERX BIOPHARMA SIGNS OPTION AGREEMENT FOR AMPLIGEN WITH FUJISAWA PHARMACEUTICAL COMPANY
Company Receives Initial Payment in Potentially Multi Million Dollar Distribution Agreement for CFS Treatment


1/30/2004 HEMISPHERX BIOPHARMA FINISHES PHASE 3 CFS CLINICAL TRIAL
Completion of Placebo-Controlled Phase 3 Stage Represents Important Clinical Milestone


1/26/2004 HEMISPHERX BIOPHARMA REPORTS PUBLICATION SUGGESTING EFFICACY OF AMPLIGEN IN TREATING MYOCARDITIS VIRUS
Data Show Ampligen Superior to Both Recombinant and Pegelated Interferons for Life – Threatening Inflammation of the Heart


1/20/2004 HEMISPHERX BIOPHARMA ANNOUNCES JOINT WEST NILE VIRUS CLINICAL PROGRAM WITH NEW YORK HOSPITAL
Program, led by Nationally-recognized Infectious Disease Expert, to Test Efficacy of Alferon N as a New Drug Treatment


1/13/2004 Hemispherx Biopharma Announces Joint SARS Clinical Program with Vanderbilt University
Program to Evaluate the Potential Efficacy of Alferon N in the Treatment of SARS; New Gene Signature Diagnosis will Accelerate Therapeutic Intervention


1/8/2004 HEMISPHERX BIOPHARMA ACCELERATES NEW ORAL SARS PREVENTION PROGRAM Company's Oral Interferon Could Potentially Stem Next Outbreak of Disease

1/6/2004 HEMISPHERX BIOPHARMA TO CONVENE LEADING SCIENTIFIC EXPERTS TO LAUNCH INNOVATIVE 2004 CLINICAL PROGRAMS
Company attracts industry experts to focus clinical activities in the areas of SARS, West Nile Virus and HIV-Prevention


12/18/2003 HEMISPHERX BIOPHARMA EXPANDS APPLICATIONS FOR ALFERON THROUGH NEW MANUFACTURING AGREEMENT
Manufacturing Partnership Could Give Company Ability to Deliver Alferon LDO Orally for SARS


11/20/2003 HEMISPHERX BIOPHARMA APPOINTS DR. ANTONIO ESTEVE TO ITS BOARD OF DIRECTORS
Executive Committee Member of Key European Partner to Play Active Role in European Development of Alferon®


11/18/2003 HEMISPHERX BIOPHARMA THIRD QUARTER EARNINGS ANNOUNCED …Cash Position Increased and the Total Shareholders Equity Increased

11/13/2003 HEMISPHERX BIOPHARMA BIOTERROR PROGRAM COVERED AT FEDERAL BIODEFENSE RESEARCH FY 2004 CONFERENCE
Company’s Bioterror Treatment/Prevention Initiative Introduced in Project BioShield


11/10/2003 HEMISPHERX BIOPHARMA REPORTS NEW SARS DATA ON ALFERON AT THE 14TH INTERNATIONAL ANTIVIRAL SYMPOSIUM
One of the Most Effective Antiviral Compounds Tested to Date Now Becomes Lab Standard


11/5/2003 HEMISPHERX BIOPHARMA TO PRESENT NEW DATA ON ALFERON IN SARS AT IX INTERNATIONAL ANTIVIRAL SYMPOSIUM AND WORKSHOP
European Symposium To Be Held November 9-12, 2003


10/30/2003 HEMISPHERX BIOPHARMA COMPLETES $ 4,142,357 PRIVATE PLACEMENT
Third Multi Million Dollar Transaction in Year 2003 to Further Expand Alferon N Sales Program and Prepare for Ampligen NDA Filing


10/29/2003 HEMISPHERX BIOPHARMA APPOINTS DR. LUC MONTAGNIER, LEADING HIV EXPERT, TO SERVE ON SCIENTIFIC ADVISORY BOARD
Growing Recognition for Potential of Ampligen attracts Discoverer of HIV/AIDS Virus & Pioneer in Disease Treatment and Prevention


10/23/2003 HEMISPHERX BIOPHARMA APPOINTS PROFESSOR JAMES J. RAHAL, M.D., WEST NILE VIRUS EXPERT, TO SCIENTIFIC ADVISORY BOARD
Clinical Expertise in New Biodefense and Emerging Infectious Disease Area


10/21/2003 HEMISPHERX BIOPHARMA APPOINTS JACK M. GWALTNEY JR., M.D. TO SCIENTIFIC ADVISORY BOARD
International Expert on Topical Delivery of Broad-Spectrum Antivirals to Protect Large, at Risk, Populations


10/16/2003 HEMISPHERX BIOPHARMA APPOINTS ANTHONY KOMAROFF, M.D., HARVARD UNIVERSITY PROFESSOR AND LEADING CFS EXPERT TO SCIENTIFIC ADVISORY BOARD

10/14/2003 HEMISPHERX BIOPHARMA EXPANDS SARS PREVENTION/TREATMENT INITIATIVE
Prior to Anticipated Fall/Winter Outbreak also widens Distribution and Clinical Networks


9/15/2003 HEMISPHERX BIOPHARMA REPORTS ON ANNUAL MEETING
.…Capital Structure Doubles and Company reconfirms its Year 2003 Targets
…. Present Management Re-elected by Large Majority


9/4/2003 HEMISPHERX BIOPHARMA SIGNS AGREEMENT WITH GUANGDONG MEDICINE GROUP CORPORATION
Partnership for Clinical Program, Sales and Distribution in the People’s Republic of China for the Treatment of HCV and HIV


8/20/2003 HEMISPHERX BIOPHARMA SECOND QUARTER EARNINGS ANNOUNCED
Cash Position Increased and the Total Shareholders Equity Improved


8/18/2003 HEMISPHERX BIOPHARMA ENTERS INTO SALES AND MARKETING AGREEMENT WITH ENGITECH FOR ALFERON N
Agreement Provides Nationwide Sales Team for Alferon N


8/11/2003 HEMISPHERX BIOPHARMA ENTERS INTO AGREEMENT WITH THE JOHANN WOLFGANG GOETHE UNIVERSITY, INSTITUTE OF VIROLOGY
Independent US Scientific Panel Recommends Further Evaluation of Ampligen® for SARS


8/4/2003 HEMISPHERX BIOPHARMA RECEIVES NEW PATENTS FOR ORAL DOSED BROAD-SPECTRUM IMMUNE ACTIVATORS
Company Prepares Applications to Bioterror and Emerging Infectious Diseases Granting Programs


7/29/2003 HEMISPHERX REPORTS AMPLIGEN PREVENTS DESTRUCTION OF NERVE CELLS AND INCREASES SURVIVAL RATES IN FLAVIVIRUS INFECTION
Independent Study shows Ampligen® demonstrates Broad-Based Potential in Virus Classes associated with Bioterror and West Nile Virus


7/15/2003 HEMISPHERX REPORTS NEW HIV TREATMENT DATA ON AMPLIGEN AT THE 2nd IAS CONFERENCE ON HIV PATHOGENESIS AND TREATMENT
Initial Therapeutic Data on Immune Response Now Confirmed over Significantly Longer Observation Period


7/11/2003 HEMISPHERX COMPLETES $ 5,500,000 PRIVATE PLACEMENT
Second $ 5.5 Million Transaction in 4 Months to Accelerate Market Development and Additional Commercial Approvals


6/30/2003 HEMISPHERX NET ASSETS RISE BY $ 2.8 MILLION
Shareholder Equity increases over Previous Reporting Quarter


6/23/2003 HEMISPHERX BIOPHARMA ANNOUNCES INDEPENDENT STUDY THAT SHOWS AMPLIGEN® SUPERIOR TO OTHER ANTIVIRALS
Prof. Neyts receives prestigious Prusoff Award for research potentially applicable to SARS


6/19/2003 HEMISPHERX ENTERS AGREEMENT WITH BUSINESS ASIA CONSULTANTS
An American/Chinese Cooperative Agreement to Accelerate SARS program


6/17/2003 HEMISPHERX SIGNS LETTER OF INTENT WITH GUANGDONG MEDICINE CO.
A Chinese Collaboration Partner for SARS Program


6/2/2003 HEMISPHERX REPORTS DATA ON ALFERON AT SARS CONFERENCE
Clinical Study of Relative Safety Profiles of Natural IFN over Recombinant IFN suggests less Drug Induced Morbidity


5/29/2003 HEMISPHERX PARTICIPATES IN ANTI-SARS FORUM
Hemispherx Gives Keynote Speech at “Anti-SARS Forum”
Organized by Sino-American Pharmaceutical Association


5/27/2003 HEMISPHERX FILED PATENT APPLICATIONS TO COMBAT SARS
Hemispherx Confirms Filing Patent Applications for the Use of Alferon N Injection® and Ampligen® for treating SARS


5/21/2003 SARS: Newly NIH Sponsored Studies of Potential Therapies for SARS now Finds Hemispherx’ Ampligen® among the Most Active from a Large Pool of 70 (Seventy) Drug Candidates

5/21/2003 Hemispherx Announces Acceleration of Manufacturing Process of Alferon N Higher Product Demand Anticipated in View of Increased Incidence of HPV Reported by Federal Agencies

5/20/2003 HEMISPHERX ANNOUNCES FIRST QUARTER RESULTS
…..Overall Operating Expenses Decrease 22% Over Prior Year.
…..Fully Commercialized Immune-Based Antiviral Product Acquired.


5/19/2003 Hemispherx Reports Positive Independent Study Results of Alferon N in the Treatment of Pig Coronavirus (Animal Model of SARS) Amsterdam Group proves Koch’s Postulates on Human Coronavirus (SARS) Clinical Study Shows Significantly Greater Survival Rates of Treated Piglets in Natural Outbreaks Low Dose Alferon N Effective within 4 days of Treatment

5/13/2003 Hemispherx Initiates Collaboration on SARS with Genome Institute of Singapore Company launches efforts to combat SARS with its lead Products Ampligen® and Alferon® N

5/8/2003 Hemispherx Biopharma: New NIH Sponsored Data on Ampligen presented with West Nile Virus Ampligen effective in reducing morbidity and mortality in two different animal studies New FDA Regulations may permit accelerated commercialization

5/5/2003 HEMISPHERX BIOPHARMA ENTERS INTO THERAPEUTIC AGREEMENT FOR AMPLIGEN® WITH THE CENTER FOR CELL AND GENE THERAPY AT BAYLOR COLLEGE OF MEDICINE Immune stimulation through dendritic cells holds promise for increasing cancer remission rates.

4/29/2003 HEMISPHERX REPORTS EXPANDED HIV DATA ON AMPLIGEN AT THE 16th INTERNATIONAL CONFERENCE ON ANTIVIRAL RESEARCH Mean Duration of S.T.I. with Ampligen is 25+ weeks vs. 13 weeks for the Control Group. Increase in CD8+ cells in the Ampligen arm also observed.

4/22/2003 HEMISPHERX BIOPHARMA EXTENDS DISTRIBUTOR AGREEMENT FOR ALFERON N Injection - - - - National Institute of Health reports 5.5 Million new genital Human Pamplona Virus outbreaks each year Center of Disease Control reports related Sexually Transmitted Diseases healthcare costs second only to HIV

4/15/2003 Hemispherx Biopharma Announces Fourth Quarter and Year 2002 Results Cash and Equivalents Increased 6.0 Million Dollars by Recent Transactions G&A and Cash Loss Reduced Phase III CFS Clinical Trials Targeted for Completion in 2003 Commercial Expansion of Fully Natural Interferon Proceeding on Target

4/8/2003 Webcast Alert: Hemispherx BioPharma, Inc. Announces HEB Presentation at Redchip Partners New York Investor Conference 2003 Webcast

3/26/2003 HEMISPHERX BIOPHARMA APPOINTS DAVID FEDORCZYK DIRECTOR OF CLINICAL AND STATISTICAL AFFAIRS - - - - History Of Successful Record In FDA Commercial Filings

3/24/2003 HEMISPHERX BIOPHARMA APPOINTS DR. JAMES KNILL VICE PRESIDENT OF CLINICAL DEVELOPMENT OF THE HIV/AIDS DIVISION - - - - - Former High Ranking VP At Squibb Dr. Knill Has Long Track Record Of Successful Completion Of Trials For Large Volume Drugs

3/20/2003 HEMISPHERX BIOPHARMA TO PRESENT AT THE STRATEGIC RESEARHC INTSTITUTES FIRST ‘siRNA’ CONFERENCE - - - - - Conference To Be Held March 24-25, 2003 At Hilton La Jolla, California

3/18/2003 REBROADCAST OF HEMISPHERX’S MARCH 18, 2003 CONFERENCE CALL AVAILABLE ON COMPANY’S WEBSITE OR VIA TELEPHONE REPLAY

3/13/2003 HEMISPHERX TO HOST CONFERENCE CALL ON TUESDAY, MARCH 18, 2003 AT 11:00AM EST Call to focus on Recent Acquisition, Funding and Forward Commercialization Strategies

3/12/2003 HEMISPHERX ACQUIRES RIGHTS FOR THE ONLY FDA APPROVED NATURAL ALPHA INTERFERON DRUG Company Completes a $5,500,000 Private Placement Conference Call to be Held On Tuesday, March 18, 2003 at 11:00am EST

3/6/2003 Hemispherx Biopharma to Present New Interim Clinical Data Regarding Phase IIB Study in HIV/AIDS at the 16th International Conference on Antiviral Research

2/12/2003 Expanded Clinical Data on AmpligenÒ in HIV Disease to be presented at the 16th International Conference on Antiviral Research Phase II B Study Evaluates Experimental Immunotherapy in “Holiday” Period when Antiviral Cocktails are Discontinued

1/31/2003 Hemispherx Presents New Data on Long-term, Post-trial Effects of RNA-based Ampligen(R) for Treatment for Chronic Fatigue Syndrome At Sixth Annual American Association of Chronic Fatigue Syndrome Conference January 31 - February 2, Chantilly, Virginia

1/24/2003 HEMISPHERX ANNOUNCES TAGLICH BROTHERS RELEASE OF UPDATED RESEARCH REPORT

1/22/2003 REBROADCAST OF HEMISPHERX’S JANUARY 21, 2003 CONFERENCE CALL AVAILABLE ON COMPANY’S WEBSITE OR VIA TELEPHONE REPLAY

1/17/2003 HEMISPHERX SCHEDULES CONFERENCE CALL TO REVIEW RECENT DEVELOPMENTS IN CLINICAL TRIAL EXPANSION, STRATEGIC PARTNERSHIP SUPPORT, FUNDING AND THE OVERALL COMMERCIALIZATION PROCESS

1/15/2003 Hemispherx Biopharma’s International Team of Clinical Researchers to Present New Data on Experimental Treatment of CFS “Expanded Access” Program with Ampligen® Includes 10 Treatment Centers in USA

1/15/2003 HEMISPHERX FILES WITH REGULATORS TO REGISTER 5 MILLION SHARES OF STOCK TO SUPPORT CLINICAL TRIAL EXPANSION

1/15/2003 OFFUTT SECURITIES UPDATES INDEPENDENT RESEARCH COVERAGE ON HEMISPHERX BIOPHARMA, INC.

12/18/2002 Rebroadcast of Hemispherx's December 18, 2002 Conference Call Available On Company’s Website or Via Telephone Replay

12/17/2002 Hemispherx to Host Conference Call on Recent Presentation at the 2002 DART Conference and Other Recent Developments Call Scheduled for Wednesday, December 18, 2002 at 11:00 AM Eastern Standard Time

12/17/2002 Hemispherx Presents New Data from Phase IIB Clinical Trial of RNA-based Ampligen® for Structured Treatment Interruption in HIV at DART Conference Ampligen® Study Indicates Prolonged Time Off AIDS Drugs Without Viral Rebound

12/16/2002 Hemispherx Files New US Patent Application on Immune-Based Alternative Treatment to HIV/AIDS Designed to protect ‘sanctuary’ regions of the body where virus hides and mutates into drug resistant strains.

12/9/2002 HEMISPHERX BIOPHARMA COMPLETES FULL ENROLLMENT OF ITS PHASE III CLINICAL TRIAL FOR CHRONIC FATIGUE SYNDROME (CFS) First Ever Completely Enrolled Phase III Clinical Trial for Disorder Affecting Over 500,000 Americans Surpasses Enrollment Target; Data Analysis Expected in 2003.

11/25/2002 Hemispherx Biopharma Invited to Present New Anti HIV Data at DART Conference: Phase IIB Clinical Trials of Strategic Treatment Intervention Major Drug Development in Antiretroviral Research (DART) Conference 2002 in Naples, Florida, Tuesday, December 17

11/20/2002 Hemispherx Biopharma, Inc. Adopts Stockholder Rights Plan

11/18/2002 Hemispherx Biopharma and Sigma-Aldrich Enter Agreement to Produce Hemispherx’s RNA-based Ampligen® in U.S.

11/15/2002 Hemispherx Announces Third Quarter Results Four Robust Advance-Stage Clinical Programs Accelerate as Revenues Increase. ----- Cash And Cash Equivalents Increased over Prior Nine Month Period

11/4/2002 Hemispherx Biopharma RNA Drug Technology Targets New Molecular Defects Uncovered in Prostate Cancer National Human Genome Research Pinpoints First Specific Gene Which Confers High Risk for Prostate Cancer Prostate 'Cancer Susceptibility Gene' is New Therapeutic Target

10/21/2002 HEMISPHERX BIOPHARMA PROFILED ON TOP10MICROCAPSTOCKS.COM Website Focuses on Analysis and Tracking Micro Cap Companies in Various Industries

10/9/2002 HEMISPHERX BIOPHARMA RNA DRUG TECHNOLOGY PIPELINE SHOWS THERAPEUTIC PROMISE IN U.S. GOVERNMENT SPONSORED RESEARCH
Specific New Inhibitory Effects Demonstrated on Bioterror–type Agents


9/3/2002 Hemispherx Biopharma Will Be Presenting at The Wall Street Analyst Forum in New York on September 9, 2002

8/19/2002 Hemispherx Biopharma Receives Letter of Intent for Potential Multimillion-dollar Investment by Royal Family of United Arab Emirates Understanding Announced at Annual Meeting in Philadelphia Global Technology Expands as Company-held Patents Approach the 400 Mark Clinical Trial for HIV and Hepatitis C Set to Start in Spain

8/15/2002 HEMISPHERX ANNOUNCES SECOND QUARTER RESULTS Cash and Cash Equivalents Up 22% - Operating Losses Reduced By Over 15% - Three Major Clinical Trails Expanded

7/30/2002 HEMISPHERX ANNOUNCES DETAILS ON WALL STREET REPORTER ROUNDTABLE SCHEDULED FOR WEDNESDAY JULY 31ST AT 2 PM EST Critical Scientific And Investment Related Issues In The Biotech Sector Will Be Discussed By A Panel Of Peers

7/25/2002 HEMISPHERX ANNOUNCES CONFERENCE CALENDAR Hemispherx Biopharma to Present at Several Scientific and Financial Conferences

7/11/2002 HEMISPHERX SCHEDULES CONFERENCE CALL TO REVIEW NEW DATA PRESENTED AT THE INTERNATIONAL AIDS CONFERENCE IN BARCELONA.

7/11/2002 HEMISPHERX REPORTS AMPLIGEN DATA DEMONSTRATING A MEDIAN HAART-FREE (STI) INTERVAL OF 25+ WEEKS AT INTERNATIONAL AIDS CONFERENCE IN BARCELONA Median Duration of Strategic Treatment Intervention (STI) with Ampligen is 25+ weeks vs. 7 weeks for the control group.

7/11/2002 HEMISPHERX REPORTS NEW AMPLIGEN DATA DEMONSTRATING A MEDIAN 0.5 LOG DROP IN VIRAL LOAD AT INTERNATIONAL AIDS CONFERENCE IN BARCELONA Ampligen as an adjunct to HAART decreases HIV RNA levels by 0.50 Log after a median duration of 4.5 months.

7/1/2002 Hemispherx Announces Annual Shareholders Meeting To Be Held August 14th, 2002

6/18/2002 HEMISPHERX BIOPHARMA RECEIVES NOTIFICATION OF ACCEPTANCE OF ITS TWO LATE BREAKER ABSTRACTS FOR THE XIV INTERNATIONAL AIDS CONFERENCE. Abstracts cover latest developments in the Company’s HIV/AIDS Clinical Trials for Salvage Therapy and Strategic Treatment Intervention (STI)

6/10/2002 Hemispherx Biopharma Receives New Patent In Europe For Oral Dosed Broad-Spectrum Immune Activators

6/5/2002 Hemispherx Biopharma Europe S.A. Completes Agreement With Laboratorios Del Dr. Esteve S.A. Cash Infusion, Distribution, and Clinical Trials Provided in Accord

5/16/2002 AUDIO WEB REPLAY OF HEMISPHERX’S MAY 16, 2002 CONFERENCE CALL AVAILABLE ON COMPANY’S WEBSITE

5/15/2002 HEMISPHERX ANNOUNCES FIRST QUARTER RESULTS REVENUE INCREASED-NET LOSS REDUCED BY 40% New Strategic Partnership in Europe is Disclosed

5/15/2002 HEMISPHERX TO HOST CONFERENCE CALL ON FIRST QUARTER RESULTS AND NEW HIV/AIDS ACTIVITY Call Scheduled For Thursday, May 16, 2002 At 10:30 AM

5/1/2002 PRESIDENT/OWNER OF MAJOR INTERNATIONAL OIL EXPLORATION COMPANIES JOINS HEMISPHERX BIOPHARMA BOARD OF DIRECTORS ------ Dr. Kiani Expands Commitment Of Intellectual And Financial Resource In Field Of Clinical Immunology After Spectacular Career in Global Oil and Gas Development Projects

4/29/2002 Hemispherx Announces Formation of Committee to Initiate Search For Medical Director to Lead its HIV/AIDS Division Clinical Results To Date Accelerate Patient Accrual and Expand Programs

4/18/2002 Hemispherx and The AIDS Community Research Initiative of America -- ACRIA -- Launch Immunotherapeutic HIV/AIDS Clinical Trials in New York City Trials Will Explore Use Of Ampligen® In Both ``Salvage'' And ``Strategic Interruption'' Studies

4/8/2002 Hemispherx Announces Fourth Quarter and Full Year Results Cash And Equivalents Increased To 8.4 Million Dollars G&A And Cash Loss Reduced

4/4/2002 Hemispherx to Present Today At 1:30 PM On the American Stock Exchange Invitation On Line Conference Company Will Discuss Recent Result of HIV/AIDS Clinical Trials as Presented At Medical Conference Held in Prague, Czech Republic

3/26/2002 Hemispherx Biopharma Launches New Website

3/19/2002 Hemispherx Disseminates New Clinical Data on Experimental Treatment of Multi-Drug Resistant HIV/AIDS Virus Virus Levels Observed to Drop

3/18/2002 Hemispherx Announces Poly I:Poly C12U Increases the Control of HIV During Strategic Treatment Interruption in Chronically HIV Infected Patients Ampligen® Increases the Length of Time Before Viral ``Rebound'' Occurs

2/27/2002 Hemispherx to Present New Clinical Data on Experimental Treatment of Multi-Resistant HIV/AIDS Virus New Mechanism of Immunosurveillance Being Tested Clinically

2/22/2002 Hemispherx Defamation Trial Results in Claims of Both Parties Being Denied Jury Fails To Award Damages Against Asensio; Asensio's Counterclaims Withdrawn, Unable To Be Reintroduced

1/28/2002 Hemispherx Continues To Enroll New Clinical Investigators And Expand Clinical Trial Sites In HIV Trials Company Also Prepares To Present At Upcoming Scientific Conferences

12/4/2001 Hemispherx Comments on New Report From U.S. Agency for Healthcare Research and Quality -- AHRQ -- on Chronic Fatique Syndrome -- CFS -- CFS Is Recognized, Defined, and Number of Sufferers Are Estimated Phase III Level Ampligen® Yielded the Most Promising Results of All Therapies Surveyed

11/14/2001 HEMISPHERx ANNOUNCES THIRD QUARTER FINANCIAL RESULTS ----- Public Warrant Conversions Boost Net Worth

11/1/2001 Hemispherx Biopharma Will Announce New HIV Clinical Treatment Data On Immune Intervention during “Drug Holidays” at WHO Conference

10/17/2001 Hemispherx Awarded U.S. Patent on Novel Fusion Inhibitor of HIV

10/4/2001 HEMISPHERX REPORTS ON PROGRESS IN EUROPE -- Steady Organizational Growth Since February 2000 Prepares Company For European Trials And Product Introduction

10/2/2001 Hemispherx Scientists Report New Method To Evaluate Chronic Fatigue Syndrome

10/2/2001 Hemispherx Biopharma Announces Notice Of Warrant Expiration Date

7/24/2001 HEMISPHERX BIOPHARMA SELECTED BY MSN MONEY CENTRAL’S STOCKSCOUTER AS ONE OF HIGHEST RATED SMALL-CAP BIOTECHS

6/25/2001 HEMISPHERX BIOPHARMA SPONSORS GLOBAL AIDS FUNDRAISER AT UNITED NATIONS

6/14/2001 HEMISPHERX BIOPHARMA INITIATES TREATMENT IN TWO NEW CLINICAL STUDIES OF MULTI-DRUG RESISTANT HIV-INFECTION IN U.S.A.--Culminates 15 Year Period of Discoveries-

5/9/2001 Hemispherx Biopharma, LabCorp® combine forces for Nationwide testing in HIV Immunotherapy Clinical Trials